Advanced Healthcare Materials
15 January 2024
ACP-Mediated Phase Transformation for Collagen Mineralization: A New Understanding of the Mechanism
Songzhe Shan1, Zhenhang Tang1, Kaida Sun1, Wenjing Jin1, Haihua Pan2, Ruikang Tang3, Wei Yin4, Zhijian Xie1,*, Zhuo Chen1,* and Changyu Shao1,*
1 Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou, 310016 China
2 Qiushi Academy for Advanced Studies, Zhejiang University, Hangzhou, 310058 China
3 Department of Chemistry, Zhejiang University, Hangzhou, 310058 China
4 Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058 China
10.1002/adhm.202470006
The work in article 2302418 by Zhijian Xie, Zhuo Chen, Changyu Shao, and co-workers, confirms for the first time that amorphous calcium phosphate (ACP) particles can directly infiltrate inside fibrils and mediate the phase transformation for collagen mineralization, improving the mechanical properties of the mineralized collagen and significantly promoting dentin remineralization, which provides a new mechanistic understanding of collagen mineralization and a promising strategy for hard tissue.
Anhui Province Academy of Science and Technology, No. 128,Wanshui Road, Hi-Tech Zone, Hefei City, Anhui Province, China
+86 17354022649
service@sondii.com
IPv6 network supported
Our hours
Beijing time: 9:00-18:00
