Nature Methods
10 April 2023
Time-resolved assessment of single-cell protein secretion by sequencing
Tongjin Wu1,2, Howard John Womersley2, Jiehao Ray Wang3, Jonathan Scolnick3,4 & Lih Feng Cheow1,2
1 Department of Biomedical Engineering, College of Design and Engineering, National University of Singapore, Singapore, Singapore.
2 Institute for Health Innovation and Technology, National University of Singapore, Singapore, Singapore.
3 Singleron Biotechnologies Pte. Ltd., Singapore, Singapore.
4 Healthy Longevity Translational Research Program, Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
10.1038/s41592-023-01841-y
Capture of secreted proteins onto their source cell surfaces using an affinity matrix enables simultaneous measurement of protein secretion, cell surface proteins and transcriptomes in thousands of cells at single-cell resolution.
Our hours
Beijing time: 9:00-18:00