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  • Small Methods

  • 20 July 2022

  • Impedance-Enabled Camera-Free Intrinsic Mechanical Cytometry

  • Yongxiang Feng1, Huichao Chai1, Weihua He1, Fei Liang1, Zhen Cheng2 and Wenhui Wang1,*

  • 1 State Key Laboratory of Precision Measurement Technology and Instrument, Department of Precision Instrument, Tsinghua University, Beijing, 100084 P. R. China

    2 Department of Automation, Tsinghua University, Beijing, 100084 P. R. China

  • 10.1002/smtd.202270043

  • In article number 2200325, Wang and coworkers present a camera-free intrinsic mechanical cytometry (CFIMC) for high-throughput single-cell intrinsic mechanical characterization. The strategy of CFIMC adopts a framework that couples the impedance electrodes with the constriction channel spatially, so that the impedance signals contain the dynamic deformation of the cell squeezing through the constriction channel.

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