Loss of TIMP3 expression induces inflammation, matrix degradation, and vascular ingrowth in nucleus pulposus: A new mechanism of intervertebral disc degeneration
Yan Li1,2,† | Ting Zhang3,† | Wenjia Tian4 | Hejia Hu1,2 | Zengfeng Xin1,2 | Xiaojing Ma5 | Chenyi Ye1,2 | Kai Hang1,2 | Xiuguo Han6 | Jie Zhao6 | Weixu Li1,2,*
浙江大学医学院附属第二医院李伟栩主任医师
1 Department of Orthopedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
2 Orthopedics Research Institute of Zhejiang University, Hangzhou, China
3 Department of Radiotherapy, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
4 Department of Endocrinology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China
5 Department of Pathology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
6 Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopaedics, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China
† Yan Li and Ting Zhang contributed equally to this work.